It has been reported that Chrysanthemum indicum has an antioxidant molecule having a high scavenging activity towards ROS [13-16], its antioxidant property is likely to be associated with the mechanism underlying the protective effect of s Chrysanthemum indicum against DOX-induced mutagenicity and DNA or chromosomal damage.
However, the treatment with Chrysanthemum indicum alone sowing liver tissue with scattered intrahepatic lymphocytes some are aggregated in foci (arrows), but those are little in high dose treated group (Fig.
On the other hand, the treatment with DOX in combination with low dose of Chrysanthemum indicum showing liver tissue with foci of inflammatoiy cells (arrow), central vein congetion (*) (Fig.
Treated groups with chrysanthemum indicum (groups 3 treated with low dose), showing kidney tissue with intratubular and peritubular hemorrhages (arrow head), with moderate tubular epithelial degeneration (arrows), while the glomeruli looks normal (G) (Fig.
Groups treated with DOX in combination with Chrysanthemum indicum (group 5 for low dose) showing kidney tissue with intratubular and peritubular hemorrhages (arrow head), with moderate tabular epithelial degeneration (arrows), while the glomeruli looks normal (G) (Fig.
Modulation of doxorubicin resistance by fractions from Curcuma wenyujin and Chrysanthemum indicum in MCF-7/ADR cells
Recently, much attention has been devoted to the anticancer activity of Chrysanthemum indicum on human PC3, HL 60 and HeLa cancer cells (Li et al.
Induction of apoptosis and cell cycle arrest in human HCC MHCC97H celfs with Chrysanthemum indicum extract.