ciguatoxin


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ciguatoxin

[¦sēg·wə¦täk·sən]
(biochemistry)
A toxin produced by the benthic dinoflagellate Gambierdiscus toxicus.
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Ciguatoxin bioaccumulates up the food chain as herbivorous fish eat the algae and are themselves eaten by carnivorous fish.
We tested several samples of lionfish and have unfortunately found that an uncomfortably high percentage showed the presence of ciguatoxin in the meat," says Tadzio Bervoets of Sint Maarten's Nature Foundation.
Ciguatoxin and brevetoxins, neurotoxic polyether compound active on sodium channels.
We also assumed that although ciguatoxin can survive freezing and other food preservation methods, fish are consumed around the same time (i.
Saxitoxins, brevetoxin and its derivatives, and ciguatoxin bind to different sites of voltage-dependant sodium channels, resulting in either an inhibition or a persistent activation of the channels, with consequent increase in intracellular calcium (Kao & Walkwe 1982, Gutierrez et al.
Fishes other than shellfish, for example, often rank high as vehicles, but if vehicles associated with ciguatoxin and scombrotoxin (which are fishborne and affect only the few persons who eat the toxigenic fish) are subtracted, the numbers drop considerably.
Sira Technologies holds the patent on a solid-phase immunobead assay (S-PIA) that has been used successfully in detecting ciguatoxin and okadaic acid.
The majority of problems were related to two specific cases: consumption of raw molluskan shellfish and consumption of tropical fish which are associated with the naturally occurring ciguatoxin and scombrotoxin poisons.
Participants were asked to save fish remnants eaten by case-patients for ciguatoxin analysis at the Food and Drug Administration laboratory in Dauphin Island, Alabama (USA).
It is conceivable that events of the tsunami amplitude could potentially lead to algal bloom and accumulation of ciguatoxin in some finfish species and biotoxins in bivalve shellfish," FAO noted.
invertebrates, marine mammals, birds) limits the ability to identify the pathway of ciguatoxin production within the food chain and forewarn of likely fish and human exposure.
Assay results were positive and the ciguatoxin content of the fish sample was estimated to be 1.