clastogenesis

clastogenesis

[‚klas·tə′jen·ə·səs]
(cell and molecular biology)
The loss, addition, or rearrangement of chromosomes.
References in periodicals archive ?
Several potential carcinogenic mechanisms have been proposed, including inhibition of DNA repair enzymes, tumor promoter-like induction of proliferation, alteration of DNA methylation, and clastogenesis (Kitchin 2001).
In this review, the scope has been confined to actual data obtained from research on the modulatory effects of plant extracts on mutagenesis and clastogenesis - two genotoxic phenomena associated with carcinogenesis.
5 g/L) or high concentrations, where gene mutations and clastogenesis has been observed in several test systems (Chang et al.