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clathrin-coated pit |
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clathrin-coated pit [¦klath·rən ‚kōd·əd ′pit] (cell and molecular biology) A partially invaginated membrane structure (bud or pit) involved in receptor-mediated endocytosis consisting of a cluster of receptor proteins attached on the cytosolic side by means of adaptin molecules to the protein clathrin, which forms a lattice-shaped coating. Complete invagination of the pit and release from the membrane results in a clathrin-coated vesicle containing cargo molecules. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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