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cleavage
(redirected from cleavable)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.03 sec.
cleavage, tendency of many minerals to split along definite smooth planar surfaces determined by their crystal structure. The directions of these surfaces are related to weaknesses in the atomic structure of the mineral and are always parallel to a possible crystal face. The property of cleavage is useful in identifying a mineral species. The tendency for certain varieties of metamorphic and sedimentary rock to split along more or less smooth surfaces is sometimes referred to as rock cleavage. Flagstone, slate, and schist are noted for this property, which arises from the parallel alignment of fine, platy mineral grains, themselves displaying cleavage.

cleavage

Tendency of a crystalline substance to split into fragments bounded by plane surfaces. Cleavage surfaces are seldom as flat as crystal faces, but the angles between them are highly characteristic and valuable in identifying a crystalline material. Cleavage occurs on planes where the atomic bonding forces are weakest; for example, galena cleaves parallel to all faces of a cube. Cleavage is described by its direction (as cubic, prismatic, basal) and by the ease with which it is produced. A perfect cleavage produces smooth, lustrous surfaces. Other degrees include distinct, imperfect, and difficult. See also fracture.


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The acquisition of a highly cleavable HA converted an avirulent strain to virulence in Pennsylvania in 1983 (H5N2), Mexico in 1994 (H5N2), Italy in 1997 (H7N1), Chile in 2002 (H7N3), and Canada in 2004 (H7N3) (Table).
SGN-35 is an ADC comprised of an anti-CD30 antibody joined by an enzyme cleavable linker to a potent, synthetic drug payload, monomethyl auristatin E (MMAE), using Seattle Genetics' proprietary technology.
SGN-35 is an ADC comprised of an anti-CD30 antibody linked by an enzyme cleavable peptide linker to an auristatin derivative, monomethyl auristatin E (MMAE), using Seattle Genetics' proprietary ADC technology.
 
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