clock gene


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clock gene

[′kläk ‚jēn]
(genetics)
Any of a number of genes that interact to determine the duration of development and lifespan.
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References in periodicals archive ?
Neonatal alcohol exposure differentially alters clock gene oscillations within the suprachiasmatic nucleus, cerebellum, and liver of adult rats.
Since Andretic's findings, many researchers have sought to more clearly understand the role of the Clock gene in rhythmicity of drug addiction.
Clock genes, oscillators, and cellular networks in the suprachiasmatic nuclei.
When clock genes are disabled, though, this surge no longer occurs, and the free radicals may linger in the brain and cause more damage," first author Erik Musiek, assistant professor of neurology at the School of Medicine, said,
The clock gene PER2 and sleep problems: Association with alcohol consumption among Swedish adolescents.
AhR activation alters circadian rhythmicity and clock gene expression (Garrett and Gasiewicz 2006).
Unlike in circadian clock genes flies, in mammals it pairs were first identified, with the protein BMAL1 to turn has two protein gears on genes.
New research now shows that each skin cell contains its own clock genes which help each cell maximize its own DNA repair.
These clock genes regulate 24-hour circadian rhythms affecting hormonal, body temperature, sleep and behavioral patterns.
Some scientists also wonder whether the effects seen from disruption of clock genes are caused by the genes' roles in circadian rhythms or by some other unknown functions of the genes.
In the late 1990s, however, the use of bioluminescent reporter proteins expressed under the control of clock gene promoters revealed that circadian oscillators resided in many peripheral tissues of vertebrates and invertebrates (Balsalobre et al.
This was done in the cells by attaching a clock gene to a luciferase gene used by fireflies to glow at night, so that the cells glowed when the biological clock was activated.