clot

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Related to clot lysis: fibrinolysis, clot retraction, clot retraction test

clot

[klät]
(physiology)
A semisolid coagulum of blood or lymph.
References in periodicals archive ?
The rationale for using rt-PA for intraventricular blood clot lysis has been adequately described by Goh and Poon (14): rt-PA is thought to enhance the normal fibrinolytic process within the CSF pathways and therefore can be considered more physiologic than the previously used fibrinolytic agents (eg, urokinase).
Anticoagulation does not treat the acute thrombus; therefore, if there is a severe compromise of venous outflow or occlusion, thrombolyfic agents may be used for clot lysis (Chow et al.
It is not known whether there is a critical window for the timing of thrombolysis or the extent clot lysis needed to improve clinical outcome (Buccino et al.
This indicates that an increased proCPU concentration in plasma signifies a retardation of clot lysis and thus could parallel increased thrombo-embolic risk.
Inducible carboxypeptidase activity: a role in clot lysis in vivo.
Differences in clot lysis among patients demonstrated in vitro with three thrombolytic agents (tissue-type plasminogen activator, streptokinase and urokinase).
5) LOT differs from clot lysis time, an older term found in hematology textbooks.
The studies demonstrated in vitro, ex vivo and in vivo that inhibition of the activity of PAI enhanced clot lysis and protected against thrombosis formation without causing bleeding, the most problematic side-effect of current treatments.
After intravenous bolus injection the compounds significantly enhanced clot lysis, and on intravenous infusion, significantly prolonged time to blood vessel occlusion in a model of thrombosis.
The Company also presented results on the use of its proprietary fibrin specific monoclonal antibody as a targeting vehicle to improve clot lysis when combined with a thromboltic agent.
Results were standardized as the extent of clot lysis per mg of