clotting factor


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Related to clotting factor: hemophilia

clotting factor

[′kläd·iŋ ‚fak·tər]
(physiology)
Any of several plasma components that are involved in the clotting of blood, such as fibrinogen, prothrombin, and thromboplastin.
References in periodicals archive ?
In patients with aPTT prolongations and hemorrhagic diathesis, acquired clotting factor inhibitors have to be considered.
From these retrospective data, it appears evident that the severely injured, coagulopathic patient needs not only oxygen carrying capacity and volume from packed red blood cells, but also clotting factors from FFP in a high ratio approaching a 1:1 ratio.
Adding to the frustration is the general ambiguity of the "administration fees," an issue that troubles Donna Ligda, a clinical nurse specialist and employee of Curative Pharmacy Services, the country's third-largest hemophilia specialty pharmacy provider of blood clotting factor.
Cryo made higher doses of clotting factor available to hemophiliacs without overloading their systems.
Currently, prophylaxis for hemophilia A typically requires injections three times per week or every other day to maintain a sufficient circulating level of clotting factor, while prophylaxis in hemophilia B typically requires injections two to three times per week.
The commitment of one billion IUs of factor is intended to enable physicians to treat more than 75,000 joint bleeding episodes, more than 2,000 life threatening bleeding episodes as well as conduct thousands of elective surgical procedures that would not be possible without access to clotting factor.
If you take clotting factors off the membrane, they're thousands of times less active.
Management before the age of 21 allows a significant reduction of treatment care in the future; therefore, fast action is crucial in order to secure immediate treatment with injections of the clotting factor concentrate in adequate doses.
One major thing in the treatment of haemophilia is that there should be regular replacement therapy of the blood clotting factor that is missing.
Hemophilia A is an inherited condition that affects 1 in 5000 males and is caused by mutations in the gene that encodes for clotting factor VIII.
The severity of a persons bleeding disorder usually depends on the amount of clotting factor that is missing or not working.
People with hemophilia lack, either partially or completely, an essential clotting factor needed to form stable blood clots.