clotting factor


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Related to clotting factor: hemophilia

clotting factor

[′kläd·iŋ ‚fak·tər]
(physiology)
Any of several plasma components that are involved in the clotting of blood, such as fibrinogen, prothrombin, and thromboplastin.
References in periodicals archive ?
The WHO says hemophilia A is the most common form, referred to as classical hemophilia, which is the result of a deficiency in clotting factor 8.
A: Hemophilia is a bleeding disorder in which blood has insufficient amount of certain proteins called blood clotting factors that are needed for blood clotting or coagulation, i.
The slight reduction in clotting factor XII activity (53 IU/dL; reference interval 70-150 IU/dL) was considered secondary.
The proteins in plasma include the major clotting factors and intrinsic anticoagulants.
1,2) They report that early replacement of clotting factors is critical--but often delayed--in managing patients with massive hemorrhage.
Treatment of chronic hepatitis C with ribavirin and interferon alfa-2b in patients with hemophilia appeared to reduce patients' use of clotting factors in a small case series, reported Takashi Honda, M.
To manage the disorder, blood clotting factor is infused (injected) to replace the missing protein.
Providers incur additional costs associated with delivering clotting factor that are not separately reimbursed by Medicare.
About 3% to 4% of patients with hemophilia B, caused by a deficiency of clotting factor IX, develop inhibitors in their blood that block the efficacy of factor IX replacement therapy administered to control bleeding episodes.
The genetic material included a human clotting factor and a pig protein.
The five behaviors that qualified as high-risk were, for hemophiliacs, having received clotting factor concentrations; for men, ever having had sex with another man since 1980; ever having taken street drugs by needle since 1980; ever having traded sex for money since 1980; and ever having had sex with a person who fits any of the above descriptions.
Gene delivery to the liver, where the factor IX clotting factor is naturally produced, resulted in easily measurable levels of factor IX for the duration of the study (270 days) and no detectable antibodies or other inhibitors of factor IX.