The point-of-care coagulation monitors investigated in this study can be used to follow trends in the clotting time
and changes in heparin dosage.
Changes in blood clotting time
Lee-White in non-siliconized (P<0.
Secondary objective was to detect any changes in bleeding, clotting time
and adverse effects profile.
Prothrombinase-induced clotting time
(PiCT): Currently under consideration for FDA approval, (24) studies have demonstrated the ability of the PiCT assay to determine activities of both direct and indirect thrombin inhibitors in a linear manner over a wide concentration range.
However, decrease in milk pH will shorten clotting time
(Storry and Ford, 1982).
Hemochron Celite Activated Clotting Time
(ACT) (International Technidyne Corporation, Edison, NJ, USA).
1): (a) collection of blood into glass SSTs, (b) 45-min clotting time
, (c) centrifugation at 13008, (d) fresh serum analysis within 4 h of collection, and (e) use of Roche Modular I.
The values were plotted against the clotting time
in seconds, and the best fit line was drawn.
Biologic analyses showed disseminated intravascular coagulation with platelet count of 22,000/[micro]L, an elevated prothrombin time (54% higher than the control value), a longer activated clotting time
(51 seconds versus a control value of 34 seconds), a fibrinogen level of 0.
Of 59 patients tested, 47% had aspirin resistance, which was defined as a clotting time
of 171 seconds or less, Mark J.
Mum Sharon said: "We need to take him out of school so the machine can measure his blood's clotting time
, then we can get an accurate prescription of Waferin, which thins the blood.
In large doses (300 mg), the natural hormone DHEA was found to increase clotting time