cobalamin


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Related to cobalamin: folic acid, vitamin B12, cobalamin deficiency, Methylcobalamin

cobalamin:

see coenzymecoenzyme
, any one of a group of relatively small organic molecules required for the catalytic function of certain enzymes. A coenzyme may either be attached by covalent bonds to a particular enzyme or exist freely in solution, but in either case it participates intimately in
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; vitaminvitamin,
group of organic substances that are required in the diet of humans and animals for normal growth, maintenance of life, and normal reproduction. Vitamins act as catalysts; very often either the vitamins themselves are coenzymes, or they form integral parts of coenzymes.
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.

cobalamin

[kə′bȯl·ə·mən]
(biochemistry)
vitamin B12
References in periodicals archive ?
Our reference interval compares well with previously published values obtained by methods using immunoprecipitation of HC and subsequent measurement of cobalamin or vitamin [B.
In studies on tumor cell lines, the combination of cobalamin and ascorbic acid produced hydrogen peroxide and had a synergistic effect in decreasing mitotic counts and survival of tumor cells.
For TSH, this may reflect gradual fine-tuning of homeostatic mechanisms, whereas for cobalamin, it likely reflects gradual depletion of cobalamin stores that were generated in utero.
2]O damages the protein by producing OH-radical, with depletion of cobalamin being a secondary cause, NO should prevent only regeneration of the CH3-cbl(III) prosthetic group.
Inadequate release of protein-bound cobalamin because of impaired gastric acid and pepsin secretion
12] group, all of the serum cobalamin concentrations were obtained more than 24 hours after the last oral dose.
He cited the findings of a small study in which 18 geriatric patients with serum cobalamin levels less than 150 pmol/L and cognitive dysfunction received intramuscular injections of 1,000 [micro]g of [B.
Cobalamin deficiency was diagnosed during hospitalization.
Access) is an emerging biopharmaceutical company focused on developing a range of products primarily based upon the company's three key drug delivery technologies: Synthetic Polymer Targeted Drug Delivery System, Cobalamin Mediated Oral Drug Delivery System and Cobalamin Mediated Targeted Drug Delivery System.
It is known that certain diseased cells, notably cancer, have an elevated demand for certain vitamins, including vitamin B12, making our Cobalamin platform technology compelling for reformulations of cancer-killing agents nearing the end of their patent life," stated Jeffrey B.
Homocysteinemia(uria) may result from nutritional deficiency, cystathionine-[beta]-synthase mutations, or errors in folate and cobalamin metabolism.
Objective: The imbalance between neurotoxic cytokine tumor necrosis factor-[alpha] (TNF-[alpha]) and neurotrophic cytokines epidermal growth factor (EGF) and interleukin-6 (IL-6) plays a role in the pathogenesis of cobalamin (Cbl) deficiency-induced neuropathy.