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codon

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.01 sec.
codon: see nucleic acid nucleic acid, any of a group of organic substances found in the chromosomes of living cells and viruses that play a central role in the storage and replication of hereditary information and in the expression of this information through protein synthesis.
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codon [′kō‚dän]
(genetics)
The basic unit of the genetic code, comprising sequential, nonoverlapping three-nucleotide sequences in messenger ribonucleic acid, each of which is translated into one amino acid; 61 of the 64 codons code for a specific protein synthesis; the other 3 are stop codons that specify termination of the growing polypeptide or protein chain.


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Amyloid protein of Gerstmann-Straussler-Scheinker disease (Indiana kindred) is an 11 kd fragment of prion protein with an N-terminal glycine at codon 58.
Biologists have long held that swapping one codon for another doesn't change the resulting protein's structure, as long as both codons instruct the machinery to insert the same amino acid.
The Sec residue in selenoproteins as GSH-Px and SeP is co-translationally incorporated via a predefined UGA codon, which has a specific covalent binding capacity.
 
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