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cold agglutinin

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
cold agglutinin [′kōld ə′glüt·ən·ən]
(immunology)
A nonspecific panagglutinin found in many normal human serums which produce maximum clumping of erythrocytes at 4°C and none at 37°C.


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Patients may also present with lymphadenopathy, splenomegaly, hyperviscosity syndrome, cryoglobulinemia, peripheral neuropathy, cold agglutinin hemolysis, autoimmune thrombocytopenia, von Willebrand's disease and, in rare cases, amyloidosis.
 
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