cold agglutinin


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Related to cold agglutinin: Cold Agglutinin Titer

cold agglutinin

[′kōld ə′glüt·ən·ən]
(immunology)
A nonspecific panagglutinin found in many normal human serums which produce maximum clumping of erythrocytes at 4°C and none at 37°C.
References in periodicals archive ?
High response rate and durable remissions following fludarabine and rituximab combination therapy for chronic cold agglutinin disease.
Fulminant autoimmune cold-type hemolysis with marked elevation of monothermic cold agglutinins.
This should be contrasted with cold agglutinins which cause agglutination of RBCs.
The main differential diagnosis for immune-mediated hemolysis includes WAIHA, DHTRs, cold agglutinin disease, and DIIHA.
Abstract: A 40-year-old white male developed Mycoplasma pneumoniae pneumonia (IgM titer 1:256) as well as autoimmune hemolytic anemia due to cold agglutinins (titer of 1:512).
Abstract 0585: "Efficacy of the Terminal Complement Inhibitor Eculizumab Used Chronically in a Patient with Cold Agglutinin Diseases (CAD)," Dr.
A histogram distribution that is bimodal can be seen in various situations, such as dimorphic anemia, cold agglutinin disease, after the transfusion of normal erythrocytes into a person with abnormally sized erythrocytes, in the presence of erythrocyte fragments, or with agglutination.
The old-fashioned cold agglutinin test has a low sensitivity and specificity; an increase in titers can be seen during a variety of viral infections.
The female patient in Italy with AOSD, at the onset of her illness developed autoimmune haemolytic anaemia due to cold agglutinin.