is regarded as one of the last lines of defence against serious diseases, including pneumonia, which cannot be treated by other medicines.
was found to be the most sensitive drug (Table I).
Our results have revealed that 100% of CPE isolates were susceptible to colistin
Either international units or milligrams of the sodium salt colistimethate (the inactive prodrug) may be used, and to confuse matters further, colistin
base activity (CBA) in milligrams may also be used to define the dose.
was highly active against both ceftazidime-NS ([MIC.
3 Interestingly, in this study, all strains were found sensitive to colistin
, whereas up to 50% heteroresistance to colistin
has been reported globally.
This poster demonstrates that plazomicin was associated with improved survival and a higher microbiological response rate compared with colistin
in patients with bloodstream infections (BSI) caused by CRE.
is not commonly used in clinical practice because of its neurotoxicity and nephrotoxicity, and this antibiotic has been considered as a therapeutic option for treatment of VAP caused by MDR NFGNB.
among Gram-negative bacteria were isolated with a high rate, almost the only antibiotic that could be used for Acitenobacter strains was colistin
, carbapenem resistance was considerably high in Pseudomonas strains and ESBL positivity was observed with a high rate in Enterobacteriaceae, especially E.
The following antibiotics were included: amoxicillin, amoxicillin-clavulanic acid (AMC), piperacillin, piperacillin-tazobactam (TZP), mezlocillin, mezlocillin-sulbactam (MSU), cefazolin, cefuroxime, ceftriaxone, cefotaxime, ceftazidime, cefoperazone, cefoperazone-sulbactam (CSL), cefepime, aztreonam, moxalactam, imipenem, meropenem, panipenem, ertapenem, gentamycin, amikacin, tetracycline, minocycline, tigecycline, ciprofloxacin, levofloxacin, nitrofurantoin, fosfomycin, polymyxin B, and colistin
Over the last few year, scientists have found evidence that some bacteria have become resistant to a last resort antibiotic called colistin
, Medical Daily reported.
The emerging issue of colistin
resistance, due to the mobile plasmid-mediated lipid-A transferase gene mcr-1, was discussed by a number of presenters.