Caption: Features identified in the bone marrow that are more commonly seen in collagen vascular diseases (CVDs) compared with controls are as follows: A, Abnormal bony trabeculae (osteosclerotic in this case).
Previous Studies on Bone Marrow Biopsies in Collagen Vascular Diseases Source, y No.
Collagen vascular disease cases had more abnormal results, both increased and decreased.
Is the collagen vascular disease
well established and is the patient on appropriate therapy?
Laboratory measurements, including ESR, ANA, RF, aldolase, CPK, and SCL-70, often help to identify collagen vascular diseases as an etiology for the ILD.
Occasionally, bronchoalveolar lavage and transbronchial biopsy are revealing, especially with sarcoid, pulmonary alveolar proteinosis or to confirm active alveolitis in collagen vascular diseases.
Of note, patients with ILD due to collagen vascular diseases, particularly scleroderma, may develop pulmonary hypertension that is independent of hypoxia, but rather intrinsic to the rheumatologic disease itself.
Although most forms of collagen vascular disease
are treatable if detected before organ damage has occurred, the diseases are difficult to diagnose because symptoms are often vague and similar to those of other disorders.
8) Important risk factors for gallbladder perforation are old age (over the age of 60), male gender, previous attacks of cholecystitis, other severe systemic diseases (malignancy, diabetes mellitus, coronary arterial diseases, renal diseases, diabetes mellitus, collagen vascular diseases
, obesity, arteriosclerosis, immunosuppression and long-term use of steroids).
PAH can also occur in association with collagen vascular diseases
such as scleroderma, CREST syndrome and systemic lupus erythematosus (SLE), congenital heart diseases, HIV infection and liver disease.
Endothelial cells, which line the body's blood vessels, are often activated and damaged in cardiovascular disease, following transplantation, and in diverse inflammatory states such as lupus and other collagen vascular diseases
In my experience and in the literature, there is also no evidence that implants are associated with collagen vascular diseases
, such as lupus or rheumatoid arthritis.