collagen disease

(redirected from collagenosis)
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collagen disease:

see autoimmune diseaseautoimmune disease,
any of a number of abnormal conditions caused when the body produces antibodies to its own substances. In rheumatoid arthritis, a group of antibody molecules called collectively RF, or rheumatoid factor, is complexed to the individual's own gamma globulin
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; collagencollagen
, any of a group of proteins found in skin, ligaments, tendons, bone and cartilage, and other connective tissue. Cells called fibroblasts form the various fibers in connective tissue in the body.
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collagen disease

[′kä·lə·jən di‚zēz]
(medicine)
Any of various clinical syndromes characterized by widespread alterations of connective tissue, including inflammation and fibrinoid degeneration.
References in periodicals archive ?
Kawakami T, Saito R: Acquired reactive perforating collagenosis associated with diabetes mellitus: eight cases that meet Faver's criteria.
Faver IR, Daoud MS, Su WP Acquired reactive perforating collagenosis.
According to the ruling, the 48-year-old woman, a resident of Owariasahi, Aichi Prefecture, was admitted to the state-run hospital in April 1996 after she was diagnosed as possibly having collagenosis as she suffered from rashes and liver dysfunction.
Currently, the chip identifies antibodies associated with approximately 10 different collagenosis and vasculitis-related autoimmune diseases, including systemic and neonatal lupus and systemic sclerosis.
Patients were excluded if they had coronary artery disease, severe valvular disease, hypertrophic cardiomyopathy, chronic obstructive pulmonary disease, malignancy, congenital heart disease, chronic heart failure, cardiac rhythm other than sinus, uncontrolled hypertension prior to study, systemic disease such as collagenosis, chronic autoimmune, hemolytic, hepatic and chronic renal disease, or inadequate transthoracic echocardiographic images.
3) These include leukemic infiltration, lymphoma, lichen planus, morphea, reactive perforating collagenosis, melanoma metastases, angiosarcoma, and infections.
The spectrum of disease includes Kyrle's disease, elastosis perforans serpiginosa, perforating folliculitis, and reactive perforating collagenosis.
This chip will enable our laboratories to measure the presence of autoantibodies to various autoantigens associated with different collagenosis and vasculititis-related autoimmune diseases from a single serum sample.