The small internal diameter and thinner film reduce the column bleed
that can interfere with quantification of the higher molecular weight PAHs.
Using purifiers with indicators, and remembering to check them regularly, helps minimize GC column bleed
and extend column lifetimes while improving system sensitivity.
is the loss of lower molecular weight stationary phase pieces that are either the result of impurities in the starting polymer or the decomposition of the phase at elevated temperatures.
The company claims it uses a proprietary bonding and deactivation procedure that lowers column bleed
and reduces activity.
Bowers and Borts argue that the lack of improvement for the QIT when presented with an analyte present in a complex matrix arises because the width of the window for ion admittance to the trap allows matrix or column bleed
ions (or both) to enter with the analyte ions.
The columns are compatible with highly aqueous mobile phase and feature low column bleed
, high efficiency and rugged packing.
In this instance, the oven must be cooled at a much slower rate to allow dissipation of the column bleed
so that 'focused' condensation within the column does not occur.
Thus, the ratio of the number of ions from column bleed
or matrix background to the number of ions of the compound of interest stays the same at the time that the total analytical signal is decreased.
If the carrier gas contains even trace amounts of water or oxygen it may damage the GC column stationary phase, resulting in bad peak shape and excessive column bleed
Advantages of fast GC include reduced run times, increased sample throughput, improved signal-to-noise ratio and less column bleed
Reduced column bleed
minimizes the risk of contamination of the mass spectrometer while extending the interval between scheduled maintenance.
The low column bleed
provides increased detector sensitivity and faster baseline stabilization.