There were mucin-positive cells in the columnar epithelium
, and the columnar epithelium
protruded into the inner mucin pools (Fig.
In addition, there have been a few worrisome reports of squamous epithelium growing on top of Barrett columnar epithelium
and an inability to provide surveillance postablative therapy.
The columnar epithelium
, which covers the tentacle, also comprises three types of cells that are evenly spread over the surface without being organized into sensory papillae.
The epithelial lining of the drainage system varies from nonkeratinizing squamous epithelium (canaliculi) to cuboidal and columnar epithelium
containing interspersed mucus-secreting goblet cells (sac and duct).
The World Health Organization's histologic classification of MCTs divides these tumors into 3 broad categories: (1) mucinous cystic adenomas characterized by a single layer of columnar epithelium
with occasional micropapillae, mild epithelial dysplasia, basally located nuclei, and no mitotic figures; (2) mucinous cystic borderline tumors, which exhibit some epithelial pseudostratification, moderate epithelial dysplasia (diffuse or focal), occasional mitoses, and irregular hyperchromatic nuclei with prominent nucleoli; and (3) noninvasive mucinous cystadenocarcinomas, which have multilayered epithelia with papillary projections with high-grade dysplasia (often focal), marked nuclear atypia, and frequent mitotic figures.
2) Pseudostratified columnar epithelium
is the most common type of lining.
27] In our case, the cystic wall was lined with columnar epithelium
without lymphocyte infiltration.
Histologic and colposcopic studies have documented that in about 90% of cases the initial neoplastic events in the epithelium of the cervix take place in the area of squamous epithelium adjacent to the columnar epithelium
, known as the transformation zone.
The last line of evidence that calls into question the entirely "benign" nature of metaplastic non-goblet cell columnar epithelium
relates to the potential risk of dysplasia and carcinoma.
is usually present where the cyst lining has not been denuded.
Viral antigens were present prominently in the squamous and columnar epithelium
(Figure 1B) and in lesser amounts in fibroblasts and histiocytes in the ulcer bed or underlying the lesions.
Raman spectroscopy can differentiate normal squamous epithelium and columnar epithelium
in the cervix from squamous metaplasia, low-grade dysplasia, high-grade dysplasia, and carcinoma in situ.