comedocarcinoma


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Related to comedocarcinoma: comedonecrosis

comedocarcinoma

[¦kä·mə·dō‚kärs·ən′ō·mə]
(medicine)
A type of adenocarcinoma of the breast in which the ducts are filled with cells which, when expressed from the cut surface, resemble comedos.
References in periodicals archive ?
For example, in a metastatic lesion, the presence of solid nests and trabeculae composed of tumor cells with limited nuclear pleomorphism, punctate areas of necrosis suggestive of comedocarcinoma, or trabeculae composed of small hyperchromatic tumor cells strongly suggests the possibility of a breast origin, particularly in a female patient (9) (Figure 4, A through D).
In contrast to more typical cases of comedocarcinoma, these tumor cells lacked apocrine features, specifically abundant granular cytoplasm, but instead had scant cytoplasm that was focally clear.
In most cases, the lactiferous ducts directly connected to the Paget disease contain comedocarcinoma.