comparative genomic hybridization


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comparative genomic hybridization

[kəm¦par·əd·iv jə‚nō·mik ‚hī·brəd·ə′zā·shen]
(genetics)
A method that uses fluorescence in situ hybridization and comparison of the strength of hybridization signal to determine any differences in copy number of deoxyribonucleic acid sequences anywhere in the nuclear genome.
References in periodicals archive ?
Parallel analysis of sporadic primary ovarian carcinomas by spectral karyotyping, comparative genomic hybridization, and expression microarrays.
CAN ARRAY COMPARATIVE GENOMIC HYBRIDIZATION DIFFERENTIATE MELANOMA FROM SPITZ NEVUS?
Children with unexplained mental retardation should undergo genetic screening with comparative genomic hybridization when standard cytogenic techniques fail to detect chromosomal abnormalities, according to Dr.
Regarding the story about using comparative genomic hybridization on preimplantation cells ("It's a boy
The scope of cytogenetics includes several technologies besides fluorescence in situ hybridization (FISH), comparative genomic hybridization (CGH), and multicolor FISH.
Technologies include array comparative genomic hybridization (CGH), copy number variation (CNV), DNA methylation, ChIP-Chip, RNA splice variants, and microRNA.
To delineate the chromosomal alterations associated with ACC-HGT we used an array comparative genomic hybridization (aCGH) approach to assess 5 tumors in 4 patients.
We are delighted to announce the world's first pregnancy using real time polar body array Comparative Genomic Hybridization (CGH) and the baby is due later in the spring," the Telegraph quoted Dr Simon Fishel, from the Care Fertility Group in Nottingham, as saying.
Microarray-based comparative genomic hybridization (CGH) offers the ability to interrogate many more genomic regions in a single assay.
They enumerate the required materials, equipment, and protocols of contamination-reducing methods becoming more routine including laser-assisted cell collection, comparative genomic hybridization, and real-time gene expression analysis.
Roche's main competitor seems to be Agilent, which is also able to offer microarray products in combination with PCR products and also competes in the market for comparative genomic hybridization arrays.
In a recent study using comparative genomic hybridization and other molecular analyses.
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