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prothrombin |
Also found in: Dictionary/thesaurus, Medical, Hutchinson | 0.04 sec. |
prothrombinCarbohydrate-protein compound in plasma essential to coagulation. In response to bleeding, a complex series of clotting-factor interactions leads to its conversion by thromboplastin to thrombin, which transforms fibrinogen in plasma into fibrin. Fibrin and platelets combine to form a clot. Hemophilia is caused by a hereditary lack of one of the clotting factors. Vitamin K is needed to synthesize prothrombin, so conditions that impair the vitamin's absorption result in prothrombin deficiency and a tendency to prolonged bleeding. prothrombin [prō′thräm·bən] (biochemistry) An inactive plasma protein precursor of thrombin. Also known as factor II; thrombinogen. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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