concatamer


Also found in: Medical.

concatamer

[kən′kad·ə·mər]
(cell and molecular biology)
Two or more identical linear molecules (for example, deoxyribonucleic acid and ribonucleic acid) covalently linked in tandem.
References in periodicals archive ?
The variation involves a virus-encoded DNA nicking enzyme which cuts and separates the individual viral genomes from the resulting concatamer.
In immunoRCA, the 5' end of an oligonucleotide primer is attached to an antibody; thus, in the presence of circular DNA, DNA polymerase, and nucleotides, the rolling circle reaction produces a concatamer of circle DNA sequence copies that remain attached to the antibody.
In this "immunoRCA", the 5' end of a RCA primer is attached to an antibody; thus, in the presence of circular DNA, DNA polymerase, and nucleotides, the rolling circle reaction produces a concatamer of circular DNA sequence copies that remain attached to the antibody.
When dPCR is used, there is a unique challenge associated with quantifying sequences that may occur as concatamers (repeats of the same sequence that are present on the same molecule); concatameric sequences cannot be measured individually in different partitions.