amaurosis

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amaurosis

[‚a‚mȯ′rō·səs]
(medicine)
Total or partial blindness.
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References in periodicals archive ?
The ocular-plus blind group (n = 22) included children with ROP (n = 5), Leber's congenital amaurosis (n = 13), Nome's disease (n = 2), optic nerve hypoplasia (n = 1), and optic nerve atrophy (n = 1).
Leber's congenital amaurosis (LCA), the target of this current study, is a group of inherited blinding diseases that damages light receptors in the retina.
The AAV delivery system is successfully being used in clinical trials of Leber congenital amaurosis gene therapy that have restored vision in more than 50 adults and children who were virtually blind.
Viruses to stop blindness Experts at University College London used a very carefully modified virus to correct DNA errors in patients suffering Leber's congenital amaurosis, which slowly destroys night vision.
SPK-RPE65 received breakthrough therapy designation for the treatment of nyctalopia, or night blindness, in patients with Leber's congenital amaurosis due to mutations in the RPE65 gene.
Also reported was the identification of a target for the rare group of severe inherited disorders classed as Leber congenital amaurosis (LCA), associated with nystagmus and considerable loss of vision.
9% (n = 468) of the sample; retinal disorders, such as Leber's congenital amaurosis and rodcone dystrophies, represented 5.
Washington, July 30 ( ANI ): Scientists have isolated an elusive human gene that causes a common form of Leber congenital amaurosis (LCA), a relatively rare but devastating form of early-onset blindness.
has announced that QLT091001, an oral synthetic retinoid, has received positive opinions for two distinct Orphan Drug Designations by the European Medicines Agency (EMA) Committee for Orphan Medicinal Products (COMP) for the treatment of the inherited retinal degenerative diseases, Leber Congenital Amaurosis (LCA) and Retinitis Pigmentosa (RP).
Gene therapy restored sight in three people with an inherited form of blindness called Leber's congenital amaurosis, researchers reported online April 27 in the New England Journal of Medicine.
Kirby Center for Molecular Ophthalmology at Penn's Scheie Eye Institute, have been researching inherited retinal degenerations such as Leber congenital amaurosis (LCA), for 18 years.
Test-retest variability is central to Leber's congenital amaurosis results

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