congenital heart disease, any defect in the heart heart, muscular organ that pumps blood to all parts of the body. The rhythmic beating of the heart is a ceaseless activity, lasting from before birth to the end of life.
..... Click the link for more information. present at birth. There is evidence that some congenital heart defects are inherited, but the cause of most cases is unknown. One known cause is infection of the mother with the rubella rubella or German measles, acute infectious disease of children and young adults. It is caused by a filterable virus that is spread by droplet spray from the respiratory tract of an infected individual.
..... Click the link for more information. (German measles) virus during the first trimester of pregnancy. Among the most common congenital heart disorders are malformations in the valves and the persistence of structures that are normally closed off at birth, i.e., the ductus arteriosis (the fetal blood vessel that shunts blood from the pulmonary vein to the aorta, bypassing the heart) and the foramen ovale (the opening between the left and right atria of the fetal heart). If the malformation is severe, it will produce various symptoms of insufficient heart function, such as cyanosis (a bluish tinge to the skin), dyspnea (difficulty in breathing), fatigue, and abnormal heartbeat; valvular deformities predispose the patient to bacterial infection of the endocardium (see endocarditis endocarditis (ĕn'dōkärdī`tĭs)
..... Click the link for more information. ). Less severe malformations may not produce noticeable symptoms until later in life, and some may not require any medical attention. Many congenital heart defects that are debilitating can be corrected surgically. Other congenital anomalies, such as Down syndrome Down syndrome, congenital disorder characterized by mild to severe mental retardation , slow physical development, and characteristic physical features. Down syndrome affects about 1 in every 730 live births and occurs in all populations equally.
..... Click the link for more information. , are present in about 20% of cases of congenital heart disease. See also heart disease.

congenital heart disease

Deformity of the heart. Examples include septal defect (opening in the septum between the sides of the heart), atresia (absence) or stenosis (narrowing) of one or more valves, tetralogy of Fallot (with four components: ventricular septal defect, pulmonary valve stenosis, right ventricular enlargement, and positioning of the aorta so that it receives blood from both ventricles), and transposition of the great vessels (so the pulmonary and systemic circulations each receive blood from the wrong side of the heart). Such defects can prevent enough oxygen from reaching the tissues, so the skin has a bluish cast. Many are fatal if not corrected surgically soon after birth—or, rarely, before birth, if detected prenatally. Abnormalities of the large vessels are usually less serious (see aorta, coarctation of; ductus arteriosus).