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congo red |
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congo red [′käŋ·gō ′red] (organic chemistry) C32H22N6Na2O6S2An azo dye, sodium diphenyldiazo-bis-α-naphthylamine sulfonate, used as a biological stain and as an acid-base indicator; it is red in alkaline solution and blue in acid solution. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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16-18) Identification of amyloid is based on three criteria: (1) Congo red binding and green birefringence under polarized light, (19) (2) a fibril structure on electro microscopy, (20) and (3) confirmation of the characteristic cross beta-pleated sheet on x-ray crystallography and infrared spectroscopy. Sections stained with Congo red dye demonstrated the characteristic yellow and apple-green birefringence, and the lesion had the beta-pleated sheet structure and antiparallel conformation by low-angle x-ray diffraction, typical of amyloidosis. |
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