connexins


Also found in: Medical.

connexins

[kə′nek·sənz]
(cell and molecular biology)
A group of transmembrane proteins that form the intermembrane channels of gap junctions; they are used by inorganic ions and most small organic molecules to pass through cell interiors.
References in periodicals archive ?
Functional role of connexins and pannexins in the interaction between vascular and nervous system.
7-11 The role of mitochondrial ion channels such as Bcl-2 in apoptosis is well-documented and, it is also likely that additional ion channels formed by the connexin 43 (Cx43) protein may play a similar role in cardiac myocyte apoptosis.
Connexins 26, 32 and 43 are expressed in synoviocytes, and Cx43 is the most highly expressed connexin in normal human synovial membranes.
2+]/calmodulin-dependent protein kinases II Cx43: Connexin 43 CV: Conduction velocity DAD: Delayed afterdepolarization EAD: Early afterdepolarization ICD: Implantable cardioverter defibrillator NCX: [Na.
TEHRAN (FNA)- How does a protein called connexin put the clamps on cancer?
Impaired trafficking of connexins in androgen-independent human prostate cancer cell lines and its migration by a-catenin.
Connexins are encoded by members of a multigene family, are defined by their molecular weight, and share high homology.
Connexins form intercellular channels by combining in groups of six to form a structure called a connexon.
Pierre et Marie Curie, Paris; AP-HP Hopital Charles Foix, Centre de Recherche et Developpement, Ivry-sur-Seine, France) introduces types of gap junctions, their structural aspects, expression patterns of connexins (transmembrane proteins), and gap junction-related diseases due to mutations in connexin genes.
Connexins CX26, CX32, and CX43, that form gap junctions and provide long range cell signaling within epithelia, appear down-regulated as the expression profiles of three malignant odontogenic tumors with those of the three benign ameloblastomas.
Connexins, hearing and deafness: clinical aspects of mutations in the connexin 26 gene.