conserved sequence


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conserved sequence

[kən′sərvd ′sē·kwəns]
(evolution)
A sequence of nucleotides in genetic material or of amino acids in a polypeptide chain that has changed only slightly or not at all during an evolutionary period of time.
References in periodicals archive ?
Such an alignment generates a sequence-similarity hierarchy in which the most closely conserved sequence is listed first, thereby identifying the organisms which were most likely growing in the students' houses.
To identify regions of conserved sequence characteristics, we downloaded pair-wise alignment data from the UCSC Genome Browser version Human/Cow (bosTau4), Mouse/Cow (bosTau4), and Human/Mouse (mm9) with pair-wise alignments.
Hammerhead ribozymes, as based on the Haseloff and Gerlach model (Nature, 1988), consist of a catalytic core made up of a highly conserved sequence of 24 nucleotides that cleave substrate RNAs.
These reagents contain shorter highly conserved sequence regions improving assay specificity, and the probes are non-cleavable which allows post-PCR melt curve analysis.
Juvaris' universal influenza vaccine has demonstrated significant induction of immunity with a novel construct of M2e, which is a conserved sequence found on all influenza A strains.
HEV infection was confirmed by using nested PCR amplification of a conserved sequence within the HEV open reading frame (ORF) 2-3 overlapping region (8).
These maps will also help define conserved sequence regions greatly improving the ability to localize important new genes.
However, the patient's serum but not CSF tested positive for flavivirus RNA when a universal flavivirus reverse transcription (RT)-PCR assay that targets the conserved sequence of the NS5 region was used (3).
The terminus of the 3' NCR has a conserved sequence and secondary structure.
The duplication of a conserved sequence at the start of ORF1 and ORF2 is characteristic of caliciviruses and is seen in all 4 genera, NoV, sapovirus, lagovirus, and vesivirus (5,26-28).
For this procedure, universal morbillivirus primers based on the conserved sequence of a 457-bp fragment of the phosphoprotein gene (6,8) were used.
The 3' conserved sequence of class I integrons is characterized by antibiotic resistance gene qacE?