constitutive secretory pathway

constitutive secretory pathway

[¦kän·stə‚tüd·iv ¦sek·rə‚tȯr·ē ′path‚wā]
(cell and molecular biology)
A secretory pathway found in all cells by which transport vesicles continuously leave the Golgi apparatus and fuse with the plasma membrane, and their contents are exported to the extracellular space or used as components of the plasma membrane.
References in periodicals archive ?
Members of the family of eucaryotic, subtilisin-like endoproteases that reside in the constitutive secretory pathway, which include furin, Paired Basic Amino Acid Cleaving Enzyme 4 (PACE4), Prohormone Convertase 5 (PC5), and Prohormone Convertase 7 (PC7), are prime candidates for the endoproteolytic maturation of pro-BACE.
Furin is a eucaryotic, subtilisin-like endoprotease that localizes to the trans-Golgi network of the constitutive secretory pathway and processes a wide variety of proproteins, including the precursors for several hormones and growth factors, receptors, blood proteins, bacterial toxins, and viral glycoproreins.