contact inhibition


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contact inhibition

[′kän‚takt in·ə′bish·ən]
(cell and molecular biology)
Cessation of cell division when cultured cells are in physical contact with each other.
References in periodicals archive ?
After further research I determined that the contact inhibition and cancer resistance in naked mole rats is due to high levels of a molecule called hyaluronan between the cells.
He said that the experiments showed that when HMM-HA was removed from naked mole rat cells, they became susceptible to tumors and lost their contact inhibition.
These cells also formed cell mounds, indicating a loss of contact inhibition (the natural process of cell growth stopping once a certain density of cells is reached).