convalescent serum


Also found in: Dictionary, Thesaurus, Medical.

convalescent serum

[¦kän·və¦les·ənt ′sir·əm]
(immunology)
The serum of the blood of one or more patients recovering from an infectious disease; used for prophylaxis of the particular infection.
References in periodicals archive ?
Convalescent serum samples were available for roughly half of all culture-negative cases, and among those, nearly 90% lacked immunologic reactivity to Y pestis.
WHO director general Margaret Chan said the agency will work closely with the affected countries to stop the sale of blood used as a convalescent serum in the black market.
Surprisingly, some isolates survived in convalescent serum, raising the possibility that specific antibodies were either absent, not sufficient to elicit a response or surface proteins of GAS like immunoglobulin binding proteins and other factors than M type bound antibodies non-type specifically and rendered them ineffective for opsonophagocytosis.
Cadham to produce convalescent serum, and set out the parameters regarding which cases would be suitable for serum treatment.
Early convalescent serum collected on January 14 (10 days after illness onset) was submitted to CDC for testing and demonstrated no evidence of MARV infection by virus isolation, antigen-detection enzyme-linked immunosorbent assay (ELISA), or anti-MARV immunoglobulin M (IgM) and IgG ELISA.
SARS case definition to allow exclusion of cases with a negative convalescent serum specimen.
Of the 66 probable SARS cases, convalescent serum has been collected for 40 (61%).
the absence of antibody to SARS-CoV in convalescent serum obtained >21 days after symptom onset) have been documented for 63 cases (49 suspect and 14 probable).
The collection and testing of convalescent serum is critical for laboratory confirmation of cases that have undetermined laboratory status.
Obtaining convalescent serum samples to make a final determination about infection with SARS-CoV is critical.
positive findings based on detection of antibody to SARS-CoV in serum or evidence of virus in respiratory specimens by reverse transcriptase polymerase chain reaction analysis, or negative findings based on absence of antibody to SARS-CoV in convalescent serum obtained >21 days after symptom onset).
One patient also has had a negative convalescent serum.