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convertase |
Also found in: Medical | 0.02 sec. |
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convertase [′än·vər‚tās] (biochemistry) An enzyme that cleaves inactive protein precursors into smaller biologically active molecules. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| She has a mutant gene for prohormone convertase 1, an enzyme that activates certain proteins, including insulin, as the final step in their production. This program, in collaboration with University of Texas (UT) Southwestern Medical Center at Dallas, is focused on evaluating new approaches for reducing LDL cholesterol levels using RNAi therapeutics directed to the disease target called proprotein convertase subtilisn/kexin type 9, or PCSK9. Alnylam scientists presented pre-clinical in vivo efficacy data from its hypercholesterolemia program evaluating new approaches for reducing LDL-cholesterol levels using RNAi therapeutics directed to a disease target called proprotein convertase subtilisn/kexin type 9, or PCSK9. |
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