biopsy

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biopsy

(bīäp`sē), examination of cells or tissues removed from a living organism. Excised material may be studied in order to diagnose disease or to confirm findings of normality. Preparatory techniques depend on the nature of the tissue and the kind of study intended. Incisions may be made and total or partial lesions removed in the form of wedges or cylindrical pieces, or scrapings of the surface membranes of internal organs may be collected. Needlelike instruments may be used to pierce the tissues and remove soft inner material. Once the tissue specimen has been obtained it is fixed, i.e., membrane proteins and enzymes are stabilized and chemical and histologic analyses are carried out by pathologists. Tumors are routinely biopsied in order to determine whether they are malignant. Fine needle aspiration is a technique more readily used for certain tumors or lesions because it is less expensive and damaging than traditional surgical biopsy.

biopsy

[′bī‚äp·sē]
(pathology)
The removal and examination of tissues, cells, or fluids from the living body for the purposes of diagnosis.

biopsy

1. examination, esp under a microscope, of tissue from a living body to determine the cause or extent of a disease
2. the sample taken for such an examination
References in periodicals archive ?
52,64,70,71) A meta-analysis by Pieri et al (68) that included 42 patients with pleomorphic LCIS on core biopsy from 5 studies showed an upgrade rate of 36% (15 of 42; 14 invasive carcinomas, 1 DCIS).
Studies show that up to 10-33% of specimens diagnosed by core biopsy may have an associated invasive component on the final surgical specimen.
Immunohistochemical stains on the core biopsy showed the tumour cells were positive for TTF-1, PAX8, CK7 and occasional cells were positive for thyroglobulin.
Additional immunohistochemical stains were performed in order to compare the pattern of staining in the resection to the prior biopsy: "The histomorphology and immunohistochemical staining pattern, including the positive brachyury nuclear expression, were identical to the findings in the core biopsy supporting the diagnosis of dedifferentiated chordoma, extra-axial type," the study concluded.
Percutaneous core biopsy for renal masses: Indications, accuracy and results.
58), and particularly so if a core biopsy rather than a vacuum assisted biopsy was performed (P < 0.
The use of core biopsy imprint cytology in the 'one-stop' breast clinic.
Subsequent core biopsy has shown this to be a caseating granuloma in keeping with Tuberculosis infection.
Sometimes it is necessary to perform a core biopsy of the lump, which removes a small piece of the lump using a slightly larger needle.
For both sexes, either a fine-needle aspiration (FNA) biopsy or core biopsy of the mass is often performed to obtain a pathologic diagnosis.
There are two situations considered absolutely contra indicative to SLN biopsy--these are cases with clinically proven axillary lymph involvement (N1) after ultrasonography and fine-needle aspiration cytology (FNAC) or core biopsy, and patients with hypersensitivity or allergy to blue dye and/or radio-colloid material used to perform SLN biopsy.
Core biopsy under US guidance showed abundant thick collagen bands containing epitheloid fibroblasts and a stroma with small capillarysized and larger muscularised blood vessls, some of which contained peri-vascular lymphocytic inflammatory cells.