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corepressor |
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corepressor [¦kō·ri‚pres·ər] (cell and molecular biology) A certain metabolite which, through combination with a repressor apoprotein produced by a regulator gene, can cause the binding of the protein to the operator gene region of a deoxyribonucleic acid chain. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Corepressor requirement and thyroid hormone receptor function during Xenopus development. Studies have identified about 30 different estrogen-receptor-enhancing, or coactivator, proteins, and a few receptor-suppressing, or corepressor, proteins. NH-3 binds to the ligand-binding domain of the TRs, with selectivity for TR[[beta] over TR[alpha], leading to a conformational change of the receptor with release of TR corepressors. |
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