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Constriction or narrowing, as of the heart or blood vessels.



the narrowing of a physiological opening or the lumen of a tubular organ. Examples of the former include stenosis of the left atrioventricular orifice of the heart, or mitral stenosis. Examples of the latter include stenosis of the intestine, trachea, bronchi, arteries, or pylorus of the stomach (pylorostenosis).

Stenoses may be congenital (developmental anomalies) or acquired, in which case they may be caused by a tumor or by scarring following an inflammatory process, ulcer, or trauma. Organic strictures are distinguished from functional stenoses, which result from a spasm of the musculature. Severe stenosis hampers the movement of blood, food, and air, and consequently the musculature of the organ located above the stenosis hypertrophies (compensated stenosis). Later, muscle tone decreases, the lumen of the organ above the stricture enlarges substantially, and the movement through the narrowed part becomes disrupted (decompensated stenosis).

Stenosis is treated surgically by enlarging the affected orifice, as in some cases of heart disease, by passing a bougie through the structure involved, by excising the constricted part, or by performing plastic surgery.

References in periodicals archive ?
Diagnostic accuracy of 64-slice computed tomography for detecting angiographically significant coronary artery stenosis in an unselected consecutive patient population--comparison with conventional invasive angiography.
Angiography demonstrated acute stent thrombosis, a 90% left anterior descending coronary artery stenosis, a 70% stenosis of the left circumflex coronary artery and associated severe inferior hypokinesis.
Predictive value of remnant-like particle cholesterol as an indicator of coronary artery stenosis in patients with normal serum triglyceride levels.
The development of coronary collaterals is mainly determined by the severity of coronary artery stenosis and the duration of myocardial ischemic symptoms (7, 29).
Coronary artery calcification: its relationship to coronary artery stenosis and myocardial infarction.
However using carotid intimal:media thickness (IMT) screening has a sensitivity < 80% for the presence of coronary artery stenosis > 50%.
Comparison between coronary angioplasty and coronary artery bypass surgery for the treatment of unprotected left main coronary artery stenosis (the Bologna Registry).
SAN FRANCISCO -- The extent of coronary artery stenosis and the number of cardiac events declined in 19 patients with ischemic cardiomyopathy who had pacemakers implanted, compared with 19 similar patients who did not receive pacemakers.
Food and Drug Administration (FDA) for use in the treatment of hemodynamically significant coronary artery stenosis, including in-stent restenosis and complex type C lesions, for the purpose of improving myocardial perfusion.
Of the women studied, 819 (45%) had coronary artery stenosis that exceeded 50%.
The authors propose that transthoracic echocardiographically measured EFT is significantly correlated with the severe multiple coronary artery stenosis in patients with known CAD and EFT could be used for in the risk stratification of those patients.

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