Perfusion

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perfusion

[pər′fyü·zhən]
(physiology)
The pumping of a fluid through a tissue or organ by way of an artery.

Perfusion

 

a method of passing physiological solutions, blood, blood substitutes, or other fluids through the blood vessels of an organ, a part of the body, or the entire body. Perfusion may be performed on organs completely removed from the body or on organs within the body but isolated from the general vascular system. Widely used in experimental physiology, it permits preservation of the vital activities of organs for a certain period, enabling the study of organ functions and of the effect of hormones, mediators, enzymes, and medicinal substances on physiological systems and the entire body. The method is used in various branches of surgery, including transplantation of organs and tissues. Perfusion of the entire body is used, for example, during heart surgery.

The term “perfusion” also designates the supplying of blood to organs of the body under natural conditions (for example, perfusion of the kidneys, brain, or other organs), which is determined by the state of cardiac activity and local vascular tonus.

References in periodicals archive ?
Level of NOS in coronary perfusion effluents was determined using an NOS assay kit (Nanjing Jiancheng Bioengineering Institute, Nanjing, China) with a spectrophotometer (Bio-RAD, USA) at 530 nm according to manufacturer's instructions with modifications as described by Ma et al.
Our study indicated that human PAMP did not significantly alter the coronary perfusion pressure, heart rate and contractile force (p>0.
Existing predictors of successful resuscitation include coronary perfusion pressure (22,23) and end-tidal C[O.
The team's studies concluded the two-thumb method produced significantly higher systolic blood pressure, higher coronary perfusion pressure and a higher sternal compression force than the two-finger method, thus efficiently increasing blood flow to the heart and the body.
showed that the AutoPulse generated 33% greater coronary perfusion pressure (CPP) than manual CPR conducted by medical residents.
During diastole, the cuffs inflate sequentially to push blood toward the heart, resulting in augmented diastolic central aortic pressure and increased coronary perfusion pressure.
In an in-hospital human trial, the AutoPulse(TM) product increased coronary perfusion pressure in arrest victims to above levels needed for a return to spontaneous circulation while manually performed CPR did not.
Nasdaq: VASO) announced today that a new study on EECP therapy entitled "Effects of Enhanced External Counterpulsation on Stress Radionuclide Coronary Perfusion and Exercise Capacity in Chronic Stable Angina Pectoris" was published in this month's edition of The American Journal of Cardiology (Vol.