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corticosterone

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corticosterone (kôr'təkōstĕr`ōn), steroid hormone hormone, secretory substance carried from one gland or organ of the body via the bloodstream to more or less specific tissues, where it exerts some influence upon the metabolism of the target tissue.
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 secreted by the outer layer, or cortex, of the adrenal gland adrenal gland or suprarenal gland , endocrine gland (see endocrine system) about 2 in. (5.1 cm) long situated atop each kidney. The outer yellowish layer (cortex) of the adrenal gland secretes about 30 steroid hormones, the most important of
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. Classed as a glucocorticoid, corticosterone helps regulate the conversion of amino acids into carbohydrates and glycogen by the liver, and helps stimulate glycogen formation in the tissues. Corticosterone is similar in structure, although somewhat less potent, than the other glucocorticoids cortisol cortisol or hydrocortisone, steroid hormone that in humans is the major circulating hormone of the cortex, or outer layer, of the adrenal gland.
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 and cortisone cortisone , steroid hormone whose main physiological effect is on carbohydrate metabolism. It is synthesized from cholesterol in the outer layer, or cortex, of the adrenal gland under the stimulation of adrenocorticotropic hormone (ACTH).
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. It is produced in response to stimulation by the pituitary substance adrenocorticotropic hormone adrenocorticotropic hormone , polypeptide hormone secreted by the anterior pituitary gland. Its chief function is to stimulate the cortex of the adrenal gland to secrete adrenocortical steroids, chief among them cortisone.
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 (ACTH). In some species, but not in humans, corticosterone is the predominant glucocorticoid secreted by the adrenal. It is a precursor in the synthesis of aldosterone aldosterone , steroid secreted by the cortex of the adrenal gland. It is the most potent hormone regulating the body's electrolyte balance. Aldosterone acts directly on the kidney to decrease the rate of sodium-ion excretion (with accompanying retention of water),
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, another adrenal cortical steroid.
corticosterone [‚kȯrd·ə′käs·tə‚rōn]
(biochemistry)
C21H30O4A steroid hormone produced by the adrenal cortex of vertebrates that stimulates carbohydrate synthesis and protein breakdown and is antagonistic to the action of insulin.


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Sullivan had previously found that odours associated with their mother suppress the release of stress hormone corticosterone in rat pups.
CS induced significant hyperglycaemia, glucose intolerance, increase in plasma corticosterone levels, gastric ulcerations, male sexual dysfunction, cognitive deficits, immunosuppression and mental depression.
11) Also, it was shown that low frequency magnetic fields induces a significant increase in the level of corticosterone in blood plasma.
 
 
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