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corticosterone |
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corticosterone (kôr'təkōstĕr`ōn), steroid hormone hormone, secretory substance carried from one gland or organ of the body via the bloodstream to more or less specific tissues, where it exerts some influence upon the metabolism of the target tissue. ..... Click the link for more information. secreted by the outer layer, or cortex, of the adrenal gland adrenal gland (ədrēn`əl) or suprarenal gland ..... Click the link for more information. . Classed as a glucocorticoid, corticosterone helps regulate the conversion of amino acids into carbohydrates and glycogen by the liver, and helps stimulate glycogen formation in the tissues. Corticosterone is similar in structure, although somewhat less potent, than the other glucocorticoids cortisol cortisol (kôr`tĭsôl') or hydrocortisone, ..... Click the link for more information. and cortisone cortisone (kôr`tĭsōn'), steroid hormone whose main physiological effect is on carbohydrate metabolism. ..... Click the link for more information. . It is produced in response to stimulation by the pituitary substance adrenocorticotropic hormone adrenocorticotropic hormone (ədrē`nōkôr'təkōtrŏp`ĭk) ..... Click the link for more information. (ACTH). In some species, but not in humans, corticosterone is the predominant glucocorticoid secreted by the adrenal. It is a precursor in the synthesis of aldosterone aldosterone (ăl'dōstĭrōn`), steroid secreted by the cortex of the adrenal gland. ..... Click the link for more information. , another adrenal cortical steroid. |
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Female rats injected with PFOS have a disturbed estrous cyclicity and increased serum corticosterone levels with decreasing serum leptin levels. Researchers studying seed-caching willow tits found that blood concentrations of corticosterone double during the worst winter months. Adult rodents stressed or immunosuppressed by cold, isolation, cyclophosphamide, corticosterone, or bacterial endotoxin contract fatal encephalitis, even when an attenuated viral strain is given (29). |
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corticosterone
