corticotropin-releasing hormone


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Related to corticotropin-releasing hormone: CRH, Corticotropin-releasing factor

corticotropin-releasing hormone

[‚kȯrd·ə·kō′trō·pən ri¦lēs·iŋ ‚hȯr‚mōn]
(biochemistry)
A substance produced by the hypothalamus that stimulates the pituitary gland to produce adrenocorticotropic hormone (ACTH). Abbreviated CRH.
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Psychological stress increased corticotropin-releasing hormone mRNA and content in the central nucleus of the amygdala but not in the hypothalamic paraventricular nucleus in the rat.
Corticotropin-releasing hormone (CRH) in the teleost fish Oreochromis mossambicus (tilapia): in vitro release and brain distribution determined by a novel radioimmunoassay.
CRH haplotype as a factor influencing cerebrospinal fluid levels of corticotropin-releasing hormone, hypothalamic-pituitary-adrenal axis activity, temperament, and alcohol consumption in rhesus macaques.
Corticotropin-releasing hormone (CRH) is a peptide with 41 amino acid residues that has been localized to paraventricular nucleus of the hypothalamus.
The dexamethasone-suppressed corticotropin-releasing hormone stimulation (LDDST-CRH) [1] test was initially proposed to be more accurate in confirming hypercortisolism than the standard low-dose dexamethasone-suppression test (LDDST) for the diagnosis of Cushing syndrome (2).
In stressed mice, corticotropin-releasing hormone, nerve growth factor, neurotensin, substance P and mast cells are recruited hierarchically to induce neurogenic skin inflammation, which inhibits hair growth.
The investigators noted both that stress-related hormones, including substance P and corticotropin-releasing hormone, stimulate sebum production, and that, as a general principle, stress slows wound healing (Arch.
That finding suggests that the entire "fight-or-flight" stress-response system based on corticotropin-releasing hormone (CRH) dates back to a common ancestor of vertebrates and insects.
Effects include suppression of hypothalamic gonadotropin-releasing hormone by corticotropin-releasing hormone.
The new agents block the binding of corticotropin-releasing hormone (CRH), thus interrupting the neurohormonal cascade that leads to release of cortisol, epinephrine, and norepinephrine from the adrenal glands.
As discussed in the sidebar, both corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP) can stimulate the release of adrenocorticotropic hormone (ACTH) and, hence, corticosterone release from the adrenal glands.

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