Coumarin


Also found in: Dictionary, Medical, Wikipedia.

coumarin

[′kü·mə·rən]
(organic chemistry)
C9H6O2 The anhydride of o-coumaric acid; a toxic, white, crystalline lactone found in many plants and made synthetically; used in making perfume and soap. Also known as 1,2-benzopyrone.

Coumarin

 

a lactone of o-coumarinic acid; colorless crystals with an odor of new-mown hay. Melting point, 70°C; boiling point, 291°C. It has the following structural formula:

Coumarin is readily soluble in alcohol and ether and poorly soluble in water. It occurs in glucoside form in many plant species, for example, in sweet clover and sweet grass. Coumarin is industrially prepared from salicylic aldehyde and acetic anhydride. It serves as an odor-enhancing substance in the tobacco and perfume industries.

References in periodicals archive ?
Many researchers [3, 5, 41] reviewed the most phytochemical substances with anti-diabetes activity as following flavonoids [59], quercin [50], metformin [28], quinolizidine, anthocyanin, catechin, flavone [29], phenylpropanoids, lipoic acid [23] and coumarin [33].
Seven coumarins (coumarin, coumarin-3-carboxylic acid, ellagic acid, esculetin, 4hydroxycoumarin, scopoletin, and umbelliferone) were purchased from Sigma-Aldrich (St.
Then, epoxypropoxy coumarin (EPC) was conjugated to hydrophobically modified poly (vinyl alcohol)--epoxypropoxy coumarin conjugate (HmPVA) by the reaction between the epoxy groups of EPC and the hydroxyl group of HmPVA (Fig.
Khan's team decided to check on the coumarin content of a wide variety of food products.
DTI and DFXaI have many advantages compared with coumarins, including rapid onset of anticoagulation, no dietary restrictions, few drug-drug interactions, and more predictable pharmacokinetics.
This is expanded upon in chapter 3, Resinous Resources, and also discusses the concern with coumarin containing plants.
The principle is similar to that of dye lasers, which also amplify light using dissolved organic molecules--not proteins, but compounds such as coumarin dyes, derived from substances in grasses that smell like freshly mowed hay.
Shortly thereafter, his early lab experiments with highly potentized cinnamic aldehyde and coumarin (a variety of cinnamon) proved capable of immunizing chicken embryos from Newcastle disease virus and later was found to be effective against avian flu H9, Sendai virus, and herpes simplex 1.
Bastaki said the Consumer Materials Laboratory conducts several tests on aromatic products including Visual inspection, Turbidity test, Determination of Essential Oil content, Determination of Ethanol Content, Determination of Methanol in relation to Ethanol content, Determination Propan-1-ol, Determination of Diethyl Phthalate content, Determination of Bitrex content, and Determination of Allergic substances such as Amyl Cinnamal, Benzyl Alcohol, Cinnamyl Alcohol, Citral, Eugenol, Hydroxy-citronellal, Isoeugenol, Amylcin-namyl Alcohol, Benzyl Salicylate, Cinnamal, Coumarin and Geraniol.
And studies have discovered that high levels of coumarin can cause liver damage in sensitive people.
His fever subsided, and he was discharged a few days later while continuing to receive acenocoumarol, an oral coumarin anticoagulant.
A synthetic version of coumarin is the drug Warfarin.