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cowpox |
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cowpox, infectious disease of cows caused by a virus related to the virus of smallpox. Also called variola, it is characterized by pustular lesions on the teats and udder. Cowpox is transmitted by contact, inducing a mild infection of the hands in persons who milk infected cows. The fact that such persons had immunity to smallpox led Edward Jenner Jenner, Edward, 1749–1823, English physician; pupil of John Hunter. His invaluable experiments beginning in 1796 with the vaccination of eight-year-old James Phipps proved that cowpox provided immunity against smallpox. ..... Click the link for more information. to attempt vaccination vaccination, means of producing immunity against pathogens, such as viruses and bacteria, by the introduction of live, killed, or altered antigens that stimulate the body to produce antibodies against more dangerous forms. ..... Click the link for more information. with this virus, instead of using the dangerous method of vaccinating with material from the sores of smallpox. Jenner's method was successful and is the basis of the modern vaccination against smallpox. Horses and sheep may contract a similar disease. |
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DNA virus isolates from tissue culture samples used to test GreeneChip performance Virus Genus Sealpoxvirus 1 * Parapoxvirus Pseudocowpox virus ([dagger]) Parapoxvirus Orf virus ([dagger]) Parapoxvirus Cowpox virus ([dagger]) Orthopoxvirus Human herpesvirus ([dagger]) * Simplexvirus Gallid herpesvirus 1 ([dagger]) Iltovirus Human adenovirus E (HAdV-4) ([double dagger]) Mastadenovirus Human adenovirus C (HAdV-5) ([double dagger]) Mastadenovirus * University of Florida, Gainesville, FL, USA. In 1796, an English doctor discovered that patients who had recovered from a cattle disease called cowpox were immune to the more dangerous smallpox. The new vaccine, called MVA85A by researchers, consists of weakened cowpox virus that has been genetically engineered to make a protein normally found on the surface of M. |
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