Epithelioid DMMs are composed of cuboidal
to polygonal cells that histologically resemble mesothelial cells in well-differentiated DMM, and the correct diagnosis of DMM is strongly suspected on the basis of the hematoxylin-eosin histology, in many cases.
Cysts were lined by a tall columnar epithelium, which in some areas was pseudostratified, or by low cuboidal
to flattened cells (Fig 10).
The glands are mostly round and lined by cuboidal
cells, which can have a prominent nucleolus.
Cells were cuboidal
to polygonal in shape, with moderate amounts of foamy eosinophilic cytoplasm, well-defined cellular borders and roundto-oval nuclei, with coarsely clumped chromatin and a prominent central nucleolus (Figs 5 and 6).
The epithelial component consists of ductal and nonductal cells that can be spindle-shaped, squamous, stellate, plasmacytoid, oncocytoid, cuboidal
, or clear.
The lining in some cysts displays papillary proliferation of cuboidal
or hobnail cells with either eosinophilic or basophilic cytoplasm; in some other cysts, the lining may be composed of clear cells in single or multiple layers but, in contrast to multilocular cystic RCC, without any mural clear cell clusters or nodules.
In contrast, IDC-P has cuboidal
cells, cribriform pattern with rounded lumina, and micropapillary tufting without fibrovascular cores.
Organization and differentiation of cells begin after 96 hours; transitional epithelium is transformed into a layer of low cuboidal
cells, which then differentiate into ciliated and goblet cells.
The cells lining the structures can vary from columnar and pseudostratified to focally cuboidal
with eosinophilic cytoplasm.
5) The typical cellular features of well-differentiated epithelioid MM are medium to large polygonal, cuboidal
, or round cells with moderate or abundant eosinophilic cytoplasm and a constant nuclear to cytoplasmic ratio.
The tumor was composed of tubulopapillary and cystic formations or nests of cuboidal
to columnar epithelial cells that had variable nuclear polarity and cellular crowding, moderate anisokaryosis, and occasional mitotic figures.
Individual nonciliated low cuboidal
tumor cells had well-defined borders and bland nuclei that were uniform in size (figure 2, B).