cutaneous reaction


Also found in: Medical.

cutaneous reaction

[kyü′tā·nē·əs rē′ak·shən]
(medicine)
Any change in the outer layers of the skin, as in sunburn or the rash in measles.
Any immediate or delayed immune reaction in the skin resulting from antigen-antibody interaction.
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References in periodicals archive ?
Continuous activation of neutrophils, coupled with extensive circulating immune complexes, may predispose the host to a severe neutrophilic cutaneous reaction (3).
Hand-foot syndrome is a cutaneous reaction involving redness, peeling, blisters and intense pain on the palms of hands or the soles of feet.
Employing a simple strategy to evaluate the cutaneous reaction of an EPP patient to the laparoscopic light source gave maximal reassurance that laparoscopic cholecystectomy would not provoke intra-peritoneal complications.
PCA reaction: An IgE-dependent cutaneous reaction was generated by sensitizing the skin with an intradermal injection of anti-DNP IgE followed 48 h later with an injection of DNP-HSA into the mice tail vein.
Containing more than 35,000 adverse reactions, drug eruptions and cutaneous reaction patterns, the book includes prescription and over-the counter drugs and well as biologics and supplements.
Severe cutaneous reaction was defined as: diffuse maculopapular rash with vesicles, limited number of bullae or superficial ulceration of mucous membranes limited to one site (grade 3); or the presence of generalised bullous lesions, SJS, or toxic epidermal necrolysis (grade 4).
The patient experienced infiltration at the site of the intravenous hirudin infusion during his therapy and subsequently developed a cutaneous reaction at this site.
Cutaneous Reaction Patterns to Drugs Clinical Pattern Selected Drug Examples Acneiform lithium, corticosteroids, androgens Lichenoid thiazides, antimalarials, captopril Fixed drug eruption tetracyclines, sulfonamides, barbiturates Morbilliform beta-lactam antibiotics, calcium channel blockers Urticarial beta-lactam antibiotics, aspirin Pityriasis rosea-like captopril, gold Pigmentation minocycline, antimalarials, bleomycin Subacute lupus-like hydrochlorothiazide, terbinafine Systemic lupus-like procainamide, hydralazine, minocycline Serum sickness-like cefaclor, minocycline Pemphigus-like captopril, penicillamine Pseudoporphyria naproxen, furosemide Photosensitivity doxycycline, thiazides, sulfonylureas Source: Dr.
Differentiating a serious reaction from one that is less serious may be difficult, particularly when evaluating a patient with a cutaneous reaction.
Bardin stressed, it's vital to stop allopurinol when a cutaneous reaction occurs--and to never reintroduce the drug.
Grade 3 cutaneous reactions characterized by bullous, blistering, and exfoliating lesions occurred in 6 (0.