cybrid


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cybrid

[′sī·brəd]
(genetics)
A hybrid cell produced by fusing a cell nucleus with a cell of the same or a different species whose nucleus has been removed; some are able to proliferate. In plants, an individual produced following fusion of protoplasts from different species with complete elimination of the chromosomes of one of the species.
References in periodicals archive ?
2] consumption rates of osteosarcoma cybrid cells carrying healthy (control) or 11,778 LHON mutant mitochondrial DNA were measured with a Seahorse XF-24 system (Seahorse Biosciences, currently Agilent Inc.
2004) Leber hereditary optic neuropathy mtDNA mutations disrupt glutamate transport in cybrid cell lines.
Inheritance of organelle genomes in citrus somatic cybrids.
8993T>G mutant osteosarcoma 143B cybrid generated MIMP at the same levels as the parental wild-type cells (Wojewoda et al.
Wallace, "Functional analysis of lymphoblast and cybrid mitochondria containing the 3460, 11778, or 14484 Leber's hereditary optic neuropathy mitochondrial DNA mutation," The Journal of Biological Chemistry, vol.
This review focuses on the potential role of mitochondrial DNA (mtDNA)-related mitochondrial dysfunction in the late-onset, sporadic neurodegenerative diseases and describes the cybrid technique, a research tool useful for studying mtDNA genotype-phenotype relationships.
During the Council meeting, ministers were invited to participate in a tabletop exercise called EU CYBRID 2017 which was driven by a scenario focusing on countering hybrid/cyber threats.
Two cybrid cell lines carrying 100% wild-type and 100% A3243G mutant mtDNA (25A and 25D, respectively) were made by fusion of human mtDNA-deficient [rho.
The CYBRID exercise organised by Estonia, currently holding the EU Presidency, for tomorrows defence minister meeting is highly topical and deserves our praise.
State-of-the-art techniques, such as cybrid analysis of electron transport chain defects in the differentiation of nuclear encoded or mitochondrial encoded defects, are also included in this thin book.
EU Defence Ministers today participate in EU CYBRID 2017, a strategic table-top cyber defence exercise.