cyclamate


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cyclamate

(sī'kləmāt', –mət), any member of a group of salts of cyclamic acid (cyclohexanesulfamic acid). The sodium and calcium salts were commonly used as artificial sweetenerssweetener, artificial,
substance used as a low-calorie sugar substitute. Saccharin, cyclamates, and aspartame have been the most commonly used artificial sweeteners. Saccharin, a coal-tar derivative three hundred times as sweet as sugar, was discovered in 1879.
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 until 1969, when their use was banned by the U.S. Food and Drug Administration after reports that ingestion of large quantities of cyclamates appeared to cause cancer in some animals. There is no evidence that cyclamates are associated with cancer in humans.

cyclamate

[′sī·klə‚māt]
(organic chemistry)
The calcium or sodium salt of cyclohexylsulfamate, an artificial sweetener.
References in periodicals archive ?
The sugar substitutes market is also segmented by composition into HIS - Stevia, Aspertame, Cyclamate, Sucralose, Saccharin, Ace-K; LIS- D-Tagatose, Sorbitol, Maltitol, Xylitol, Mannitol, Erythritol.
Group E served as experimental group and was given sodium cyclamate 60mg/kg/day through oral gavage tube for two months.
A few additives once assumed to be safe, such as cyclamate salts and sulfites, are now banned or no longer considered GRAS.
Identification of the cyclamate interaction site within the transmembrane domain of the human sweet taste receptor subunit T1R3.
The disclosing tablets of bacterial plaque used were composed of alkaline fuchsin 2%, sodium saccharin, lactose, sodium cyclamate and excipients, whose function is to stain the bacterial plaque on the teeth apparently clean, with a contrasting color (bright red), facilitating to localize the bacterial plaque on the teeth surface.
11) Caloric sweeteners include fructose, sorbitol, mannitol, xylitol, lactose, maltodextrin, and sucrose; and cyclamate, saccharin, acesulfame-K, stevioside, sucralose and aspartame (a combination of phenylalanine and aspartic acid) are some of the non-caloric sweeteners.
Cyclamate has a major metabolite, cyclohexylamine, which causes testicular atrophy and at high doses, it has unwanted cardiovascular effects (Bopp and Price, 2001).
There are two types of high-intensity sweeteners: artificial sweeteners--such as alitame, cyclamate, aspartame, neotame, potassium acesulfame (Ace K) and saccharin--and natural high-intensity sweeteners extracted from various plant sources--such as stevia and luo han guo (monk fruit).
1968: The SAI launches the International Sugar Research Foundation (ISRF) to help it scrutinize the safety of rival sweeteners cyclamate and saccharin.
Artificial sweeteners such as saccharin, cyclamate, aspartame and sucralose rapidly emerged as low-calorie, tooth-friendly sugar alternatives.
Particularly compelling are the chapters on artificial sweeteners, which blend descriptions of aggressive advertising campaigns with details of backlash against products like saccharin and cyclamate.
Sweeteners with alitame, cyclamate, and steviol glycosides are not approved as food ingredients in the United States but can be found in countries by sheer negligence.