Inhibitor

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Related to cyclooxygenase inhibitor: prostaglandin inhibitor, Cyclooxygenase 2 inhibitor

inhibitor

[in′hib·əd·ər]
(aerospace engineering)
A substance bonded, taped, or dip-dried onto a solid propellant to restrict the burning surface and to give direction to the burning process.
(chemistry)
A substance which is capable of stopping or retarding a chemical reaction; to be technically useful, it must be effective in low concentration.

Inhibitor

 

a circuit having m + n inputs and a single output, at which a signal can appear only when there are no signals on the m inputs (inhibiting). The other n inputs (principal) form one of the two logic connections, “AND” or “OR.” Inhibitors are used extensively in computers. They are very often understood to be a circuit having a single principal input and a single inhibiting input. A signal appears at the output of such a circuit when a signal is present on the principal input but there is none on the inhibiting input. Such an inhibitor is called an anticoincidence gate; its conventional representation is given in Figure 1.

Figure 1. Block diagram of an anticoincidence gate (inhibitor) with m — 1 and n 1:(A) principal input, (Q) inhibiting input, (Ga) anticoincidence gate

inhibitor

A substance added to paint to retard drying, skinning, mildew growth, etc. Also see corrosion inhibitor, inhibiting pigment, drying inhibitor.
References in periodicals archive ?
While majority of studies examining the anti-inflammatory actions of this agent have focused on its role as a cyclooxygenase inhibitor, our data suggest that the interference by indomethacin with cyclooxygenase function during inflammatory challenge by LPS leads to up-regulation in the generation of PAF.
1) Treatment of OA cartilage with commonly utilized cyclooxygenase inhibitors increases LTB4 production, which is associated with a marked change in the transcription of multiple cytokine and growth factor dependent genes which are prerequisite for normal cartilage homeostasis.
Differential regulation of prostaglandin E2 and thromboxane A2 production in human monocytes: implications for the use of cyclooxygenase inhibitors.
As with all therapies, side effects with cyclooxygenase inhibitors can be expected, and lessons have been learned from the several nonprostaglandin-mediated mechanisms of action of NS-NSAIDs, demonstrated in experimental models.
As the potential for therapeutic applications of the cyclooxygenase inhibitors continues to increase, vigilance for adverse reactions and interactions of this class of drugs must also increase.
The idea is that indomethacin and other nonselective cyclooxygenase inhibitors are effective at stopping preterm labor, but they also cause substantial adverse effects such as oligohydramnios and constriction of the ductus arteriosus.

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