cox-2 inhibitor

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cox-2 inhibitor:

see nonsteroidal anti-inflammatory drugnonsteroidal anti-inflammatory drug,
a drug that suppresses inflammation in a manner similar to steroids, but without the side effects of steroids; commonly referred to by the acronym NSAID .
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References in periodicals archive ?
Differential effects of selective cyclooxygenase-2 inhibitors on endothelial function in salt induced hypertension.
NS398, a selective cyclooxygenase-2 inhibitor, induces apoptosis and down-regulates bcl-2 expression in LNCaP cells.
A cyclooxygenase-2 inhibitor impairs ligament healing in the rat.
Cyclooxygenase-2 inhibitor suppressed angiotensin II-induced secretion of thromboxane B2 in human aortic endothelial cells
For patients who are at GI risk, a selective cyclooxygenase-2 inhibitor is recommended, he continued.
85 billion into a fund to settle claims that its cyclooxygenase-2 inhibitor rofecoxib (Vioxx) was responsible for causing myocardial infarction and stroke in patients who took the drug for pain.
For instance, 17% were taking an NSAID or a cyclooxygenase-2 inhibitor, 41% were taking aspirin or clopidogrel, and 24% were on Coumadin or enoxaparin.
Investigators in an ongoing primary prevention trial of rofecoxib, a cyclooxygenase-2 inhibitor, and naproxen, a nonselective NSAID, propose to enroll 2,700 study participants and follow them for 5 years.
The Food and Drug Administration has issued a "not approvable" letter on the cyclooxygenase-2 inhibitor lumiracoxib for osteoarthritic pain.
Rofecoxib, a Cyclooxygenase-2 inhibitor, was taken off the market in response to cardiovascular safety concerns.

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