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Cytoxan
(redirected from cyclophosphamide)

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Cytoxan (sītŏk`sĭn), trade name for the drug cyclophosphamide, used to inhibit growth of tumors and rapidly proliferating cells. It is used in the treatment of leukemia, Hodgkin's disease, and lymphosarcoma and other solid tumors. A drug of great specificity, Cytoxan is activated in the body by the enzymes in certain types of tumors. Because it is also activated in such tissues as blood plasma and liver, it is a highly toxic substance. Nevertheless, it is a potent and useful chemotherapeutic agent.


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The treatment of choice is chemotherapy, which usually includes cyclophosphamide, vincristine, and prednisone.
Follicular lymphoma by Thompson, Lester D.R. / Ear, Nose and Throat Journal
ovatus) were pooled and intraperitoneally injected into 15 ddY male mice (6-15 pooled ticks per mouse) treated with the immunosuppressant cyclophosphamide.
Anaplasma phagocytophilum-infected ticks, Japan by Masuzawa, Toshiyuki / Emerging Infectious Diseases
Pharmacokinetic studies suggested a significant decrease in cyclophosphamide clearance, but no obvious affects on the other drugs.
The use of antiretroviral therapy in patients undergoing treatment ... by Yarchoan, Robert / Research Initiative/Treatment Action!
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