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cycloserine |
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cycloserine [¦sī·klō′se‚rēn] (microbiology) C3H6O2N2Broad-spectrum, crystalline antibiotic produced by several species ofStreptomyces;useful in the treatment of tuberculosis and urinary-tract infections caused by resistant gram-negative bacteria. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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9) act by inhibiting cell-wall synthesis and function (eg, penicillins, cephalosporins, bacitracin, vancomycin, cycloserine, polypeptides, antifungal polyenes), protein synthesis (eg, aminoglycosides, chloramphenicol, macrolides, tetracyclines, lincomycins), or nucleotide formation (eg, rifampin, isoniazid). Additional isolate susceptibility tests in Denver showed sensitivity to ethionamide, cycloserine, p-amino salicylic acid, clofazimine, levofloxacin, and pyrazinamide, but resistance to isoniazid, rifampin, streptomycin, amikacin/kanamycin, amoxicillin/clavulanate, and rifabutin. Cycloserine was used at a concentration of 30 [micro]g/mL (9). |
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