cytopathic effect


Also found in: Medical, Acronyms, Wikipedia.

cytopathic effect

[¦sīd·ə¦path·ik i‚fekt]
(cell and molecular biology)
A change in the microscopic appearance of cells in a culture after being infected with a virus.
Mentioned in ?
References in periodicals archive ?
Therefore, we conducted this experiment to examine the hypothesis that 4-methoxycinnamaldehyde could inhibit the cytopathic effect of RSV.
Cytomegalovirus and herpes can be identified by their characteristic cytopathic effect.
The antiviral activities of herb species-derived materials against viruses were determined by cytopathic effect (CPE) reduction method.
9] In all of these studies, early diagnosis and institution of therapy were stressed, and although still considered the "gold standard" for the detection of RSV, culture is not particularly useful for prompt diagnosis because of the prolonged time required for the production of the diagnostic cytopathic effect.
Antiviral activities of acid-soluble protein extract and fractions on herpes simplex virus (HSV-1) by inhibition of virus-induced cytopathic effect [CC.
Inhibition of the cytopathic effect (CPE) was determined spectrophotometrically using crystal violet as staining reagent for protected cells and an IEN standard (100 U/ml) as positive control.
The Kunjin MRM61C strain of WNV (9) and SHUV isolate SAE 18/09 (8) were cultured and harvested when the cytopathic effect (CPE) reached 80%.
natural interferon) has significant activity against SARS-CoV in vitro as indicated by reduction in cytopathic effect (CPE)(1).
The antiviral screening was determined by evaluating cell death caused by plant extract cytotoxicity and viral cytopathic effect as previously described (Pauwels et al.
Inhibition was quantitated by visual cytopathic effect (CPE), inhibition of the cellular uptake of the vital dye, neutral red (NR), and by virus yield reduction.
Although no macroscopic or microscopic lesions were observed at necropsy, negative contrast electron microscopy showed typical rhabdovirus-like, bullet-shaped particles in Vero cell cultures that showed a focal cytopathic effect (5).