Printer Friendly
Dictionary, Encyclopedia and Thesaurus - The Free Dictionary
1,723,455,724 visitors served.
forum mailing list For webmasters
?
New: Language forums
Dictionary/
thesaurus
Medical
dictionary
Legal
dictionary
Financial
dictionary
Acronyms
 
Idioms
Encyclopedia
Wikipedia
encyclopedia
?

cytosine

   Also found in: Dictionary/thesaurus, Medical, Acronyms, Wikipedia, Hutchinson 0.04 sec.
cytosine (sī`tōsēn'), organic base of the pyrimidine pyrimidine (pīrĭm`ĭdēn')
..... Click the link for more information.
 family. It was isolated from the nucleic acid nucleic acid, any of a group of organic substances found in the chromosomes of living cells and viruses that play a central role in the storage and replication of hereditary information and in the expression of this information through protein synthesis.
..... Click the link for more information.
 of calf thymus tissue in 1894. A suggested structure for cytosine, published in 1903, was confirmed in the same year when that base was synthesized in the laboratory. Combined with the sugar ribose in glycosidic linkage, cytosine forms a derivative called cytidine (a nucleoside), which in turn can be phosphorylated with from one to three phosphoric acid groups, yielding the three nucleotides nucleotide (n`klēətīd', ny
..... Click the link for more information.
 CMP (cytidine monophosphate), CDP (cytidine diphosphate), and CTP (cytidine triphosphate). Analogous nucleosides and nucleotides are formed from cytosine and deoxyribose. The nucleoside derivatives of cytosine perform important functions in cellular metabolism. CTP acts as a coenzyme biotin, is a member of the B complex; it was first isolated in 1935 from dried egg yolk, and its structure was established in 1942. Biotin is usually found attached to a lysine residue in certain enzymes, where it participates in reactions involving the transfer of carboxyl
..... Click the link for more information.
 in both carbohydrate and lipid metabolism; it can readily donate one of its phosphate groups to adenosine diphosphate (ADP) to form adenosine triphosphate adenosine triphosphate (ATP) (ədĕn`əsēn trī'fŏs`fāt)
..... Click the link for more information.
 (ATP), an extremely important intermediate in the transfer of chemical energy in living systems. CTP is the source of the cytidine found in ribonucleic acid (RNA) and deoxycytidine triphosphate (dCTP) is the source of the deoxycytidine in deoxyribonucleic acid (DNA). Thus cytosine is intimately involved in the preservation and transfer of genetic information.

cytosine

Organic compound of the pyrimidine family, often called a base, consisting of a single ring, containing both nitrogen and carbon atoms, and an amino group. It occurs in combined form in nucleic acids and several coenzymes. In DNA its complementary base is guanine. It or its corresponding nucleoside or nucleotide may be prepared from DNA by selective techniques of hydrolysis.


cytosine [′sīd·ə‚sēn]
(biochemistry)
C4H5ON3A pyrimidine occurring as a fundamental unit or base of nucleic acids.


How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content.
?Page tools
Printer friendly
Cite / link
Email
Feedback
? Mentioned in ? References in periodicals archive
 
A substitution of cytosine for guanine, also located in VD 1, resulted in Gln instead of Glu at amino acid position 117, as found in genotype B and strain 6BC (numbering according to the ompA amino acid sequence of the C.
Intended as a research tool, the T790M quantitative mutation assay detects the presence of a mutant thymidine base in a background of normal cytosine bases at position 2369 of the EGFR gene.
Methylation of cytosines in cytosine--guanine (CpG) dinucleotides represents a critical epigenetic DNA modification affecting gene expression and cellular function (Bird 2002).
 
Encyclopedia browser? ? Full browser
 
 
Encyclopedia
?

Disclaimer | Privacy policy | Feedback | Copyright © 2009 Farlex, Inc.
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. Terms of Use.