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cytoskeleton

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.15 sec.

cytoskeleton

System of microscopic filaments or fibres, present in the cytoplasm of eukaryotic cells (see eukaryote), that organizes other cell components, maintains cell shape, and is responsible for cell locomotion and for movement of the organelles within it. Three major types of filaments make up the cytoskeleton: actin filaments, microtubules, and intermediate filaments. Actin filaments occur as constantly changing bundles of parallel fibres; they help determine cell shape, help the cell adhere to surfaces, help the cell move, and assist in cell division during mitosis. Intermediate filaments are very stable structures that form the cell's true skeleton; they anchor the nucleus within the cell and give the cell its elastic properties.


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For example, chapter 11 describes assembly of the cellular cytoskeleton, while chapter 12 describes the mechanisms used by pathogenic bacteria to manipulate the cytoskeleton.
But most of the recovery genes Samson identified are involved with functions such as cytoskeleton remodeling, protein degradation, RNA synthesis, and lipid metabolism.
The origin of this cytoskeleton has been a mystery to biologists because more-primitive cells, bacteria, seemed to lack anything resembling a cytoskeleton or its component proteins--tubulin and actin.
 
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