cytotoxic T cell


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cytotoxic T cell

[¦sīd·ə‚täk·sik ′tē ‚sel]
(immunology)
A type of T cell which protects against pathogens that invade host cell cytoplasm, where they cannot be bound by antibodies, by recognizing and killing the host cell before the pathogens can proliferate and escape.
References in periodicals archive ?
Doherty notes that investigators are now using cytotoxic T cells to rid bone marrow transplants of viral infections and are designing vaccines, including those for AIDS, to generate these virus-killing cells.
Class I Tetramers, which are primarily used for vaccine development, accurately measure CD8 cytotoxic T cells and have been marketed primarily to biopharmaceutical
In this preclinical study, human NK cells and cytotoxic T cells were treated in vitro with interferon-alpha, with or without Ceplene.
The data, published in the December issue of Nature Biotechnology, highlights a method for modifying targets on cancer cells called antigens to facilitate activation of cytotoxic T cells -- a key component of the immune system responsible for destroying cancerous cells.
Tumor antigens are the signals to the cytotoxic T cells of the immune system that are responsible for killing tumor cells.
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